Studies on Synthetic Analgesics. IX
نویسندگان
چکیده
منابع مشابه
Animal experimentation in studying addiction to the newer synthetic analgesics.
HE term addiction, when applied to the syndrome resulting from T the prolonged use of morphine and its congeners in man, by coinmon usage involves three principal components, psychic dependence, physical dependence, and acquired toleranee. In view of the fact that the newer synthetic analgesics produce pharmacological effects, many of which are qualitatively similar to those of morphine and its...
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The hemin moiety of horseradish peroxidase (donor:hydrogen-peroxide oxidoreductase, EC 1.11.1.7) was removed and the apoprotein reconstituted with the fluorescent protoporphyrin IX. Steady-state and time-resolved fluorescence properties of the HRP(desFe) adduct were examined; the multifrequency phase and modulation method was utilized for lifetime and dynamic polarization studies. The emission ...
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Recent introduction of new analgesics into the clinic is best described as a slow process with activity classified into two main areas: improving analgesic efficacy/potency and reducing side-effect profile. This review article describes some of the recent advances with an emphasis on use in the acute setting. In this respect, opioids continue to be the mainstay (but not the only) analgesic and ...
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Leupeptins, fermentation products of various strains of Actinomycetes^ showed strong antiplasmin activity2) and were identified as being a mixture of two major components, leupeptin Ac-LL (acetyl-L-leucyl-L-leucyl-DL-argininal, 1) and leupeptin Pr-LL (propionyl-L-leucyl-L-leucyl-DL-argininal, 2), and their analogs containing isoleucine or valine in place of one or two leucine residues of 1 or 2...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1956
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.76.3_267